if planning on using IIS, you can install php and mysql add-on to IIS; however, it's easier to use asp.net and SQL on IIS, so this is not a forum for it
even w/ IIS, you might still end up to go through dns such as zoneedit... and if host more than 1 site, then still have to use VirtualHosts
remember dns is dns and VH is VH no matter what type of server or db or language script that you use so not sure what you really thinking
Have fun,
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