when putting wamp online through wamp tray icon, you grant the outsiders the access to folder www, but not your db folder; however, when any1 who gains access to your pc, either your relatives, friends, then they might unintended make a change if you have no password protection for your db access
about hackers, if they actually interested in your pc, I personally don't think any hacker would waste their time to mess w/ your pc if it does NOT have any valuable that interested them, but if you really worry about them, then you should seek help from very professional
Have fun,
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